How can we look up a string in an Excel sheet? With normal Excel code it is easy using the FIND function, but when you want to use a VBA function on all results of the find operation, you'll need a custom function:

Function FindAll(SearchRange As Range, FindWhat As Variant, _
    Optional LookIn As XlFindLookIn = xlValues, Optional LookAt As XlLookAt = xlWhole, _
    Optional SearchOrder As XlSearchOrder = xlByRows, _
    Optional MatchCase As Boolean = False) As Range
''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''
' FindAll
' This returns a Range object that contains all the cells in SearchRange in which FindWhat
' was found. The parameters to the function have the same meaning as they do for the
' Find method of the Range object. If no cells were found, the result of this function
' is Nothing.
'
''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''
Dim FoundCell As Range
Dim FoundCells As Range
Dim LastCell As Range
Dim FirstAddr As String
With SearchRange
    '''''''''''''''''''''''''''''''''''''''''''''''''''''''
    ' In order to have Find search for the FindWhat value
    ' starting at the first cell in the SearchRange, we
    ' have to find the last cell in SearchRange and use
    ' that as the cell after which the Find will search.
    '''''''''''''''''''''''''''''''''''''''''''''''''''''''
    Set LastCell = .Cells(.Cells.Count)
End With

''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''
' Do the initial Find. If we don't find FindWhat in the first Find,
' we won't even go into the code which searches for subsequent
' occurances.
''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''
Set FoundCell = SearchRange.Find(what:=FindWhat, after:=LastCell, _
    LookIn:=LookIn, LookAt:=LookAt, SearchOrder:=SearchOrder, MatchCase:=MatchCase)
If Not FoundCell Is Nothing Then
    ''''''''''''''''''''''''''''''
    ' Set the FoundCells range
    ' to the first FoundCell.
    ''''''''''''''''''''''''''''''
    Set FoundCells = FoundCell
    ''''''''''''''''''''''''''''
    ' FirstAddr will contain the
    ' address of the first found
    ' cell. We test each FoundCell
    ' to this address to prevent
    ' the Find from looping back
    ' through the range it has
    ' already searched.
    ''''''''''''''''''''''''''''
    FirstAddr = FoundCell.Address
    Do
        ''''''''''''''''''''''''''''''''
        ' Loop calling FindNext until
        ' FoundCell is nothing or
        ' we wrap around the first
        ' found cell (address is in
        ' FirstAddr).
        '''''''''''''''''''''''''''''''
        Set FoundCells = Application.Union(FoundCells, FoundCell)
        Set FoundCell = SearchRange.FindNext(after:=FoundCell)
    Loop Until (FoundCell Is Nothing) Or (FoundCell.Address = FirstAddr)
End If

''''''''''''''''''''
' Return the result.
''''''''''''''''''''
If FoundCells Is Nothing Then
    Set FindAll = Nothing
Else
    Set FindAll = FoundCells
End If

End Function

This function returns an array of ranges containing the ranges where the searched string was in. After you can perform operations on the result values like this:

Private Sub FindAndDeleteCells()
    Dim SearchRange As Range
    Dim FoundCells As Range
    Dim FoundCell As Range
    Dim FindWhat As Variant
    Dim MatchCase As Boolean
    Dim LookIn As XlFindLookIn
    Dim LookAt As XlLookAt
    Dim SearchOrder As XlSearchOrder
    
    ''''''''''''''''''''''''''
    ' Set the variables to the
    ' appropriate values.
    ''''''''''''''''''''''''''
    Set SearchRange = ThisWorkbook.Worksheets(1).Range("A1:D20")
    FindWhat = "Large"
    LookIn = xlValues
    LookAt = xlPart
    SearchOrder = xlByRows
    MatchCase = False
    
    '''''''''''''''''''
    ' Search the range.
    '''''''''''''''''''
    Set FoundCells = FindAll(SearchRange:=SearchRange, FindWhat:=FindWhat, _
        LookIn:=LookIn, LookAt:=LookAt, SearchOrder:=SearchOrder, MatchCase:=MatchCase)
    
    ''''''''''''''''''''''
    ' Display the results.
    ''''''''''''''''''''''
    If FoundCells Is Nothing Then
        Debug.Print "No cells found."
    Else
        For Each FoundCell In FoundCells.Cells
            ' Now we delete the cell and the 3 cells on the right
            FoundCell.Cells.Activate
            FoundCell.Cells.Clear
            FoundCell.Offset(0, 1).Activate
            FoundCell.Offset(0, 1).Clear
            FoundCell.Offset(0, 2).Clear
            FoundCell.Offset(0, 3).Clear
            'Delete the Cells
            ' If you only want ot delete the cells, then use this code:
            'FoundCell.Rows.Delete
            
            'Delete the entire row
            'If you want to delete the entire row then use this code:
            Dim i As Long
            For i = FoundCell.Rows.Count To 1 Step -1
                    FoundCell.Rows(i).EntireRow.Delete
            Next i

        Next FoundCell
    End If
End Sub